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A Case of Anaemia With High-Grade Splenomegaly

In tropical areas, there are a variety of parasitic and nonparasitic causes of high-grade splenomegaly. An adolescent male patient with haemoglobin E/β-thalassaemia came with high-grade splenomegaly and severe anaemia, requiring blood transfusions on a regular basis. Treatment with folic acid and an...

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Detalles Bibliográficos
Autor principal: Singh, Ranjan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187194/
https://www.ncbi.nlm.nih.gov/pubmed/35706745
http://dx.doi.org/10.7759/cureus.24908
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author Singh, Ranjan K
author_facet Singh, Ranjan K
author_sort Singh, Ranjan K
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description In tropical areas, there are a variety of parasitic and nonparasitic causes of high-grade splenomegaly. An adolescent male patient with haemoglobin E/β-thalassaemia came with high-grade splenomegaly and severe anaemia, requiring blood transfusions on a regular basis. Treatment with folic acid and antioxidant vitamins reduced the requirement for blood transfusions, brought haemoglobin levels back to near normal, and reduced splenic enlargement.  Haemoglobin E/β-thalassaemia is a haematological condition that causes anaemia and high-grade splenomegaly in the tropics. Initially, the disease was only seen in Southeast Asia, but it has since spread around the world due to migration from that region.
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spelling pubmed-91871942022-06-14 A Case of Anaemia With High-Grade Splenomegaly Singh, Ranjan K Cureus Internal Medicine In tropical areas, there are a variety of parasitic and nonparasitic causes of high-grade splenomegaly. An adolescent male patient with haemoglobin E/β-thalassaemia came with high-grade splenomegaly and severe anaemia, requiring blood transfusions on a regular basis. Treatment with folic acid and antioxidant vitamins reduced the requirement for blood transfusions, brought haemoglobin levels back to near normal, and reduced splenic enlargement.  Haemoglobin E/β-thalassaemia is a haematological condition that causes anaemia and high-grade splenomegaly in the tropics. Initially, the disease was only seen in Southeast Asia, but it has since spread around the world due to migration from that region. Cureus 2022-05-11 /pmc/articles/PMC9187194/ /pubmed/35706745 http://dx.doi.org/10.7759/cureus.24908 Text en Copyright © 2022, Singh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Singh, Ranjan K
A Case of Anaemia With High-Grade Splenomegaly
title A Case of Anaemia With High-Grade Splenomegaly
title_full A Case of Anaemia With High-Grade Splenomegaly
title_fullStr A Case of Anaemia With High-Grade Splenomegaly
title_full_unstemmed A Case of Anaemia With High-Grade Splenomegaly
title_short A Case of Anaemia With High-Grade Splenomegaly
title_sort case of anaemia with high-grade splenomegaly
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187194/
https://www.ncbi.nlm.nih.gov/pubmed/35706745
http://dx.doi.org/10.7759/cureus.24908
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