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Structural insights into G protein activation by D1 dopamine receptor

G protein–coupled receptors (GPCRs) comprise the largest family of membrane receptors and are the most important drug targets. An agonist-bound GPCR engages heterotrimeric G proteins and triggers the exchange of guanosine diphosphate (GDP) with guanosine triphosphate (GTP) to promote G protein activ...

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Detalles Bibliográficos
Autores principales:	Teng, Xiao, Chen, Sijia, Wang, Qing, Chen, Zhao, Wang, Xiaoying, Huang, Niu, Zheng, Sanduo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187227/ https://www.ncbi.nlm.nih.gov/pubmed/35687690 http://dx.doi.org/10.1126/sciadv.abo4158

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