Cohesin-dependent chromosome loop extrusion is limited by transcription and stalled replication forks

Genome function depends on regulated chromosome folding, and loop extrusion by the protein complex cohesin is essential for this multilayered organization. The chromosomal positioning of cohesin is controlled by transcription, and the complex also localizes to stalled replication forks. However, the...

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Detalles Bibliográficos
Autores principales: Jeppsson, Kristian, Sakata, Toyonori, Nakato, Ryuichiro, Milanova, Stefina, Shirahige, Katsuhiko, Björkegren, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187231/
https://www.ncbi.nlm.nih.gov/pubmed/35687682
http://dx.doi.org/10.1126/sciadv.abn7063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187231/
https://www.ncbi.nlm.nih.gov/pubmed/35687682
http://dx.doi.org/10.1126/sciadv.abn7063

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