Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?

Neutrophil extracellular traps (NETs) play a major role in intrinsic immunity by limiting and killing pathogens. Recently, a series of studies have confirmed that NETs are closely associated with vascular injury and microthrombosis. Furthermore, NETs play an important role in neuroinflammation after...

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Detalles Bibliográficos
Autores principales: Zhou, Jiru, Guo, Peiwen, Hao, Xiaoke, Sun, Xiaochuan, Feng, Hua, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187359/
https://www.ncbi.nlm.nih.gov/pubmed/35689126
http://dx.doi.org/10.1007/s12975-022-01039-y
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author Zhou, Jiru
Guo, Peiwen
Hao, Xiaoke
Sun, Xiaochuan
Feng, Hua
Chen, Zhi
author_facet Zhou, Jiru
Guo, Peiwen
Hao, Xiaoke
Sun, Xiaochuan
Feng, Hua
Chen, Zhi
author_sort Zhou, Jiru
collection PubMed
description Neutrophil extracellular traps (NETs) play a major role in intrinsic immunity by limiting and killing pathogens. Recently, a series of studies have confirmed that NETs are closely associated with vascular injury and microthrombosis. Furthermore, NETs play an important role in neuroinflammation after ischemic and hemorrhagic stroke. Neuroinflammation and microthrombosis after subarachnoid hemorrhage are key pathophysiological processes associated with poor prognosis, but their crucial formation mechanisms and interventions remain to be elucidated. Could NETs, as an emerging and important pathogenesis, be a new therapeutic target after subarachnoid hemorrhage?
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spelling pubmed-91873592022-06-17 Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage? Zhou, Jiru Guo, Peiwen Hao, Xiaoke Sun, Xiaochuan Feng, Hua Chen, Zhi Transl Stroke Res Comment Neutrophil extracellular traps (NETs) play a major role in intrinsic immunity by limiting and killing pathogens. Recently, a series of studies have confirmed that NETs are closely associated with vascular injury and microthrombosis. Furthermore, NETs play an important role in neuroinflammation after ischemic and hemorrhagic stroke. Neuroinflammation and microthrombosis after subarachnoid hemorrhage are key pathophysiological processes associated with poor prognosis, but their crucial formation mechanisms and interventions remain to be elucidated. Could NETs, as an emerging and important pathogenesis, be a new therapeutic target after subarachnoid hemorrhage? Springer US 2022-06-11 /pmc/articles/PMC9187359/ /pubmed/35689126 http://dx.doi.org/10.1007/s12975-022-01039-y Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Zhou, Jiru
Guo, Peiwen
Hao, Xiaoke
Sun, Xiaochuan
Feng, Hua
Chen, Zhi
Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title_full Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title_fullStr Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title_full_unstemmed Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title_short Neutrophil Extracellular Traps (NETs): A New Therapeutic Target for Neuroinflammation and Microthrombosis After Subarachnoid Hemorrhage?
title_sort neutrophil extracellular traps (nets): a new therapeutic target for neuroinflammation and microthrombosis after subarachnoid hemorrhage?
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187359/
https://www.ncbi.nlm.nih.gov/pubmed/35689126
http://dx.doi.org/10.1007/s12975-022-01039-y
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