Esophagitis after Clozapine Use in a 61-Year-Old Woman with Refractory Schizophrenia

Clozapine-induced esophagitis has been rarely reported. We herein report a case of a 61-year-old woman with schizophrenia who developed hematemesis, fever, and tachycardia after the initiation of clozapine. An esophagogastroduodenoscopy showed esophageal mucosal ulcerations. Her gastrointestinal sym...

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Detalles Bibliográficos
Autores principales: Ma, Sung Min, Lim, Junghyun, Jiang, Chunsu, Luca, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187460/
https://www.ncbi.nlm.nih.gov/pubmed/35693728
http://dx.doi.org/10.1155/2022/7033038
Descripción
Sumario:Clozapine-induced esophagitis has been rarely reported. We herein report a case of a 61-year-old woman with schizophrenia who developed hematemesis, fever, and tachycardia after the initiation of clozapine. An esophagogastroduodenoscopy showed esophageal mucosal ulcerations. Her gastrointestinal symptoms resolved with pantoprazole, allowing continuation of her clozapine treatment. We report here an unusual association of severe esophagitis with clozapine use.

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