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Investigating the ligand agonism and antagonism at the D(2long) receptor by dynamic mass redistribution
The signalling of the D(2) receptor (D(2)R), a G protein-coupled receptor (GPCR), is a complex process consisting of various components. For the screening of D(2)R ligands, methods quantifying distinct second messengers such as cAMP or the interaction of the receptor with β-arrestin, are commonly em...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187652/ https://www.ncbi.nlm.nih.gov/pubmed/35688965 http://dx.doi.org/10.1038/s41598-022-14311-w |