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A desirable transgenic strategy using GGTA1 endogenous promoter-mediated knock-in for xenotransplantation model
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Abl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187654/ https://www.ncbi.nlm.nih.gov/pubmed/35688851 http://dx.doi.org/10.1038/s41598-022-13536-z |