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A desirable transgenic strategy using GGTA1 endogenous promoter-mediated knock-in for xenotransplantation model

Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Abl...

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Detalles Bibliográficos
Autores principales: Ko, Nayoung, Shim, Joohyun, Kim, Hyoung-Joo, Lee, Yongjin, Park, Jae-Kyung, Kwak, Kyungmin, Lee, Jeong-Woong, Jin, Dong-Il, Kim, Hyunil, Choi, Kimyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187654/
https://www.ncbi.nlm.nih.gov/pubmed/35688851
http://dx.doi.org/10.1038/s41598-022-13536-z

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