Cargando…
A desirable transgenic strategy using GGTA1 endogenous promoter-mediated knock-in for xenotransplantation model
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Abl...
Autores principales: | Ko, Nayoung, Shim, Joohyun, Kim, Hyoung-Joo, Lee, Yongjin, Park, Jae-Kyung, Kwak, Kyungmin, Lee, Jeong-Woong, Jin, Dong-Il, Kim, Hyunil, Choi, Kimyung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187654/ https://www.ncbi.nlm.nih.gov/pubmed/35688851 http://dx.doi.org/10.1038/s41598-022-13536-z |
Ejemplares similares
-
Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs
por: Shim, Joohyun, et al.
Publicado: (2021) -
Comparison of islet isolation result and clinical applicability according to GMP‐grade collagenase enzyme blend in adult porcine islet isolation and culture
por: Kwak, Kyungmin, et al.
Publicado: (2021) -
Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation
por: Xu, Kaixiang, et al.
Publicado: (2022) -
Porcine Knock-in Fibroblasts Expressing hDAF on α-1,3-Galactosyltransferase (GGTA1) Gene Locus
por: Kim, Ji Woo, et al.
Publicado: (2012) -
No excessive mutations in transcription activator-like effector nuclease-mediated α-1,3-galactosyltransferase knockout Yucatan miniature pigs
por: Choi, Kimyung, et al.
Publicado: (2020)