FISH improves risk stratification in acute leukemia by identifying KMT2A abnormal copy number and rearrangements

Most cases of acute leukemia (AL) with KMT2A rearrangement (KMT2A-r) have a dismal prognosis. Detection of this aberration in Chinese adult patients relies on reverse transcription polymerase chain reaction (RT-PCR) and chromosome banding analysis (CBA). The fluorescence in situ hybridization (FISH)...

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Detalles Bibliográficos
Autores principales: Li, Qinlu, Xing, Shugang, Zhang, Heng, Mao, Xia, Xiao, Min, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187764/
https://www.ncbi.nlm.nih.gov/pubmed/35688861
http://dx.doi.org/10.1038/s41598-022-13545-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187764/
https://www.ncbi.nlm.nih.gov/pubmed/35688861
http://dx.doi.org/10.1038/s41598-022-13545-y

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