Development of a novel human CD147 knock-in NSG mouse model to test SARS-CoV-2 viral infection

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BACKGROUND: An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the rapidly evolving SARS-CoV-2 virus and for development of prophylactic and therapeutic strategies to combat emerging mutants. Studies show that the spike proteins of SARS-CoV and SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Badeti, Saiaditya, Jiang, Qingkui, Naghizadeh, Alireza, Tseng, Hsiang-chi, Bushkin, Yuri, Marras, Salvatore A. E., Nisa, Annuurun, Tyagi, Sanjay, Chen, Fei, Romanienko, Peter, Yehia, Ghassan, Evans, Deborah, Lopez-Gonzalez, Moises, Alland, David, Russo, Riccardo, Gause, William, Shi, Lanbo, Liu, Dongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187929/
https://www.ncbi.nlm.nih.gov/pubmed/35690792
http://dx.doi.org/10.1186/s13578-022-00822-6
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