Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice

BACKGROUND: Anti-IgLON5 disease is a rare neurological disorder associated with autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations with human IgLON5 antibodies have suggested an antibody-mediated pathogenesis, but whether human IgLON5 autoantibodies can induce...

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Detalles Bibliográficos
Autores principales: Ni, You, Feng, Yifan, Shen, Dingding, Chen, Ming, Zhu, Xiaona, Zhou, Qinming, Gao, Yining, Liu, Jun, Zhang, Qi, Shen, Yuntian, Peng, Lisheng, Zeng, Zike, Yin, Dou, Hu, Ji, Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188070/
https://www.ncbi.nlm.nih.gov/pubmed/35690819
http://dx.doi.org/10.1186/s12974-022-02520-z

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