Reciprocal regulation of NRF2 by autophagy and ubiquitin–proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles

NRF2 is the key antioxidant molecule to maintain redox homeostasis, however the intrinsic mechanisms of NRF2 activation in the context of nanoparticles (NPs) exposure remain unclear. In this study, we revealed that copper oxide NPs (CuONPs) exposure activated NRF2 pathway in vascular endothelial cel...

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Detalles Bibliográficos
Autores principales: Li, Na, Du, Hang, Mao, Lejiao, Xu, Ge, Zhang, Mengling, Fan, Yinzhen, Dong, Xiaomei, Zheng, Lijun, Wang, Bin, Qin, Xia, Jiang, Xuejun, Chen, Chengzhi, Zou, Zhen, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188091/
https://www.ncbi.nlm.nih.gov/pubmed/35690781
http://dx.doi.org/10.1186/s12951-022-01486-7

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