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Fbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells
BACKGROUND: The ubiquitin–proteasome system plays important roles in maintaining the self-renewal and differentiation of stem and progenitor cells through highly ordered degradation of cellular proteins. Fbxw11, an E3 ligase, participates in many important biological processes by targeting a broad r...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188144/ https://www.ncbi.nlm.nih.gov/pubmed/35690796 http://dx.doi.org/10.1186/s13287-022-02926-9 |