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A pump-free and high-throughput microfluidic chip for highly sensitive SERS assay of gastric cancer-related circulating tumor DNA via a cascade signal amplification strategy

Circulating tumour DNA (ctDNA) has emerged as an ideal biomarker for the early diagnosis and prognosis of gastric cancer (GC). In this work, a pump-free, high-throughput microfluidic chip coupled with catalytic hairpin assembly (CHA) and hybridization chain reaction (HCR) as the signal cascade ampli...

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Detalles Bibliográficos
Autores principales:	Cao, Xiaowei, Ge, Shengjie, Hua, Weiwei, Zhou, Xinyu, Lu, Wenbo, Gu, Yingyan, Li, Zhiyue, Qian, Yayun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188168/ https://www.ncbi.nlm.nih.gov/pubmed/35690820 http://dx.doi.org/10.1186/s12951-022-01481-y

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