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Mechanism of glycogen synthase inactivation and interaction with glycogenin

Glycogen is the major glucose reserve in eukaryotes, and defects in glycogen metabolism and structure lead to disease. Glycogenesis involves interaction of glycogenin (GN) with glycogen synthase (GS), where GS is activated by glucose-6-phosphate (G6P) and inactivated by phosphorylation. We describe...

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Detalles Bibliográficos
Autores principales:	Marr, Laura, Biswas, Dipsikha, Daly, Leonard A., Browning, Christopher, Vial, Sarah C. M., Maskell, Daniel P., Hudson, Catherine, Bertrand, Jay A., Pollard, John, Ranson, Neil A., Khatter, Heena, Eyers, Claire E., Sakamoto, Kei, Zeqiraj, Elton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188544/ https://www.ncbi.nlm.nih.gov/pubmed/35690592 http://dx.doi.org/10.1038/s41467-022-31109-6

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