Mycobacterium avium subsp. paratuberculosis exploits miRNA expression to modulate lipid metabolism and macrophage polarisation pathways during infection

Pathogenic mycobacteria including Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne’s disease, manipulate host macrophages to persist and cause disease. In mycobacterial infection, highly plastic macrophages, shift between inflammatory M1 and permissive M2 phenotypes wh...

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Detalles Bibliográficos
Autores principales: Wright, Kathryn, Mizzi, Rachel, Plain, Karren M., Purdie, Auriol C., de Silva, Kumudika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188571/
https://www.ncbi.nlm.nih.gov/pubmed/35690602
http://dx.doi.org/10.1038/s41598-022-13503-8

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