The combination of hydroxychloroquine and 2-deoxyglucose enhances apoptosis in breast cancer cells by blocking protective autophagy and sustaining endoplasmic reticulum stress

2-Deoxyglucose (2-DG) can be used in antitumour research by inhibiting glycolysis and promoting the endoplasmic reticulum stress (ERS) pathway, but its clinical application is restricted due to dose-limiting side effects and survival chance for cancer cells by protective autophagy. Therefore, our re...

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Detalles Bibliográficos
Autores principales: Zhou, Ning, Liu, Qingyun, Wang, Xiao, He, Lixin, Zhang, Tao, Zhou, Han, Zhu, Xinying, Zhou, Tianhong, Deng, Ganzhen, Qiu, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188615/
https://www.ncbi.nlm.nih.gov/pubmed/35690609
http://dx.doi.org/10.1038/s41420-022-01074-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188615/
https://www.ncbi.nlm.nih.gov/pubmed/35690609
http://dx.doi.org/10.1038/s41420-022-01074-6

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