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‘Neighbourhood watch’ model: embryonic epiblast cells assess positional information in relation to their neighbours

In many developing and regenerating systems, tissue pattern is established through gradients of informative morphogens, but we know little about how cells interpret these. Using experimental manipulation of early chick embryos, including misexpression of an inducer (VG1 or ACTIVIN) and an inhibitor...

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Detalles Bibliográficos
Autores principales: Lee, Hyung Chul, Hastings, Cato, Oliveira, Nidia M. M., Pérez-Carrasco, Rubén, Page, Karen M., Wolpert, Lewis, Stern, Claudio D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188750/
https://www.ncbi.nlm.nih.gov/pubmed/35438131
http://dx.doi.org/10.1242/dev.200295