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DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling

The earliest hematopoietic stem and progenitor cells (HSPCs) are generated from the ventral wall of the dorsal aorta, through endothelial-to-hematopoietic transition during vertebrate embryogenesis. Notch signaling is crucial for HSPC generation across vertebrates; however, the precise control of No...

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Detalles Bibliográficos
Autores principales:	Li, Yan, Tang, Chao, Liu, Fan, Zhu, Caiying, Liu, Feng, Zhu, Ping, Wang, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2022
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188753/ https://www.ncbi.nlm.nih.gov/pubmed/35502759 http://dx.doi.org/10.1242/dev.200390

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