Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance

Injections with hyaluronic acid (HA) fillers for facial rejuvenation and soft-tissue augmentation are among the most popular aesthetic procedures worldwide. Many HA fillers are available with unique manufacturing processes and distinct in vitro physicochemical and rheologic properties, which result...

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Autores principales: de la Guardia, Carola, Virno, Ada, Musumeci, Maria, Bernardin, Aude, Silberberg, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188840/
https://www.ncbi.nlm.nih.gov/pubmed/35114708
http://dx.doi.org/10.1055/s-0041-1741560
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author de la Guardia, Carola
Virno, Ada
Musumeci, Maria
Bernardin, Aude
Silberberg, Michael B.
author_facet de la Guardia, Carola
Virno, Ada
Musumeci, Maria
Bernardin, Aude
Silberberg, Michael B.
author_sort de la Guardia, Carola
collection PubMed
description Injections with hyaluronic acid (HA) fillers for facial rejuvenation and soft-tissue augmentation are among the most popular aesthetic procedures worldwide. Many HA fillers are available with unique manufacturing processes and distinct in vitro physicochemical and rheologic properties, which result in important differences in the fillers' clinical performance. The aim of this paper is to provide an overview of the properties most widely used to characterize HA fillers and to report their rheologic and physicochemical values obtained using standardized methodology to allow scientifically based comparisons. Understanding rheologic and physicochemical properties will guide clinicians in aligning HA characteristics to the facial area being treated for optimal clinical performance.
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spelling pubmed-91888402022-06-13 Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance de la Guardia, Carola Virno, Ada Musumeci, Maria Bernardin, Aude Silberberg, Michael B. Facial Plast Surg Injections with hyaluronic acid (HA) fillers for facial rejuvenation and soft-tissue augmentation are among the most popular aesthetic procedures worldwide. Many HA fillers are available with unique manufacturing processes and distinct in vitro physicochemical and rheologic properties, which result in important differences in the fillers' clinical performance. The aim of this paper is to provide an overview of the properties most widely used to characterize HA fillers and to report their rheologic and physicochemical values obtained using standardized methodology to allow scientifically based comparisons. Understanding rheologic and physicochemical properties will guide clinicians in aligning HA characteristics to the facial area being treated for optimal clinical performance. Thieme Medical Publishers, Inc. 2022-02-03 /pmc/articles/PMC9188840/ /pubmed/35114708 http://dx.doi.org/10.1055/s-0041-1741560 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle de la Guardia, Carola
Virno, Ada
Musumeci, Maria
Bernardin, Aude
Silberberg, Michael B.
Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title_full Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title_fullStr Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title_full_unstemmed Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title_short Rheologic and Physicochemical Characteristics of Hyaluronic Acid Fillers: Overview and Relationship to Product Performance
title_sort rheologic and physicochemical characteristics of hyaluronic acid fillers: overview and relationship to product performance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188840/
https://www.ncbi.nlm.nih.gov/pubmed/35114708
http://dx.doi.org/10.1055/s-0041-1741560
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