Single-domain near-infrared protein provides a scaffold for antigen-dependent fluorescent nanobodies

Small near-infrared (NIR) fluorescent proteins (FPs) are much needed as protein tags for imaging applications. We developed a 17 kDa NIR FP, called miRFP670nano3, which brightly fluoresces in mammalian cells and enables deep-brain imaging. By exploring miRFP670nano3 as an internal tag, we engineered...

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Detalles Bibliográficos
Autores principales: Oliinyk, Olena S., Baloban, Mikhail, Clark, Charles L., Carey, Erin, Pletnev, Sergei, Nimmerjahn, Axel, Verkhusha, Vladislav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189029/
https://www.ncbi.nlm.nih.gov/pubmed/35606446
http://dx.doi.org/10.1038/s41592-022-01467-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189029/
https://www.ncbi.nlm.nih.gov/pubmed/35606446
http://dx.doi.org/10.1038/s41592-022-01467-6

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