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DiMeLo-seq: a long-read, single-molecule method for mapping protein-DNA interactions genome-wide

Studies of genome regulation routinely use high-throughput DNA sequencing approaches to determine where specific proteins interact with DNA, and they rely on DNA amplification and short-read sequencing, limiting their quantitative application in complex genomic regions. To address these limitations,...

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Detalles Bibliográficos
Autores principales: Altemose, Nicolas, Maslan, Annie, Smith, Owen K., Sundararajan, Kousik, Brown, Rachel R., Mishra, Reet, Detweiler, Angela M., Neff, Norma, Miga, Karen H., Straight, Aaron F., Streets, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189060/
https://www.ncbi.nlm.nih.gov/pubmed/35396487
http://dx.doi.org/10.1038/s41592-022-01475-6