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DiMeLo-seq: a long-read, single-molecule method for mapping protein-DNA interactions genome-wide
Studies of genome regulation routinely use high-throughput DNA sequencing approaches to determine where specific proteins interact with DNA, and they rely on DNA amplification and short-read sequencing, limiting their quantitative application in complex genomic regions. To address these limitations,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189060/ https://www.ncbi.nlm.nih.gov/pubmed/35396487 http://dx.doi.org/10.1038/s41592-022-01475-6 |