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Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study
INTRODUCTION: Regulatory advisories on hydroxyzine and risk of QT prolongation and Torsade de pointes (TdP) were issued in the UK in April 2015 and Canada in June 2016. We hypothesized patients with risk factors for QT prolongation and TdP, compared with those without risk factors, would be less lik...
Autores principales: | Morrow, Richard L., Mintzes, Barbara, Souverein, Patrick C., Hallgreen, Christine E., Ahmed, Bilal, Roughead, Elizabeth E., De Bruin, Marie L., Kristiansen, Sarah Brøgger, Lexchin, Joel, Kemp-Casey, Anna, Sketris, Ingrid, Mangin, Dee, Pearson, Sallie-Anne, Puil, Lorri, Lopert, Ruth, Bero, Lisa, Gnjidic, Danijela, Sarpatwari, Ameet, Dormuth, Colin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189086/ https://www.ncbi.nlm.nih.gov/pubmed/35438459 http://dx.doi.org/10.1007/s40264-022-01175-2 |
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