Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins

The aspariginyl hydroxylase human factor inhibiting hypoxia-inducible factor (FIH) is an important regulator of the transcriptional activity of hypoxia-inducible factor. FIH also catalyzes the hydroxylation of asparaginyl and other residues in ankyrin repeat domain–containing proteins, including apo...

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Detalles Bibliográficos
Autores principales: Leissing, Thomas M., Hardy, Adam P., Chan, Hokfung, Wang, Yihua, Tumber, Anthony, Chowdhury, Rasheduzzaman, Feng, Tianshu, Coleman, Mathew L., Cockman, Matthew E., Kramer, Holger B., Berridge, Georgina, Fischer, Roman, Kessler, Benedikt M., Ratcliffe, Peter J., Lu, Xin, Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189129/
https://www.ncbi.nlm.nih.gov/pubmed/35537551
http://dx.doi.org/10.1016/j.jbc.2022.102020

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