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Dual inhibition of autophagy and PI3K/mTOR pathway as a potential therapeutic strategy against laryngeal squamous cell carcinoma

BACKGROUND: New and effective chemotherapy or targeted therapy strategies are needed against laryngeal squamous cell carcinoma (LSCC). We aimed to explore the antitumor effect of dual PI3K/mTOR inhibitor combined with autophagy suppression on LSCC and its underlying mechanism. METHODS: Hep-2 and AMC...

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Detalles Bibliográficos
Autores principales: Huang, Hui-Ying, Li, Ke-Nan, Lau, Hui-Ching, Hsueh, Chi-Yao, Cong, Ning, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189222/
https://www.ncbi.nlm.nih.gov/pubmed/35706786
http://dx.doi.org/10.21037/tcr-21-2325