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Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report

BACKGROUND: Cervical cancer is one of the most common gynecological malignancies in developing countries. But the cervical cancer patients with tumor prolapse are very rare. The treatment principle of cervical cancer has been written into the guide, while the management of cervical lumps prolapse as...

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Autores principales: Zhu, Biqing, Wu, Yaqin, Huang, Jian, He, Dan, Li, Qian, Wang, Hairong, Yang, Yongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189239/
https://www.ncbi.nlm.nih.gov/pubmed/35706782
http://dx.doi.org/10.21037/tcr-21-2109
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author Zhu, Biqing
Wu, Yaqin
Huang, Jian
He, Dan
Li, Qian
Wang, Hairong
Yang, Yongqin
author_facet Zhu, Biqing
Wu, Yaqin
Huang, Jian
He, Dan
Li, Qian
Wang, Hairong
Yang, Yongqin
author_sort Zhu, Biqing
collection PubMed
description BACKGROUND: Cervical cancer is one of the most common gynecological malignancies in developing countries. But the cervical cancer patients with tumor prolapse are very rare. The treatment principle of cervical cancer has been written into the guide, while the management of cervical lumps prolapse associated with cervical cancer is not standardized. Every doctor has different opinions on treatment strategies. Herein, we describe the three-dimensional brachytherapy treatment for massive prolapsed cervical lumps. CASE DESCRIPTION: A 48-year-old woman diagnosed with cervical cancer developed a huge cervical mass prolapsed after defecation on the second day of chemotherapy. The mass surface was continuously bleeding and unable to return to the vagina. Therefore, uterine artery embolization interventional hemostasis was performed and then three-dimensional brachytherapy treatment was applied. The mass was necrotic and shedding and then retracted into the vagina on the 7th day after implantation treatment. Finally, the patient successfully received radical radiotherapy [pelvic and abdominal cavity external beam radiotherapy-PCTV 50.4 Gy/28 F, pelvic metastatic lymph nodes PGTVn 61.0 Gy/28 F, plus vaginal three-dimensional brachytherapy-HRCTV (D90) 27.25 Gy/4 F]. CONCLUSIONS: If cervical cancer combined with tumor prolapse is inoperable, three-dimensional implants brachytherapy seems to be an adequate therapeutic option.
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spelling pubmed-91892392022-06-14 Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report Zhu, Biqing Wu, Yaqin Huang, Jian He, Dan Li, Qian Wang, Hairong Yang, Yongqin Transl Cancer Res Case Report BACKGROUND: Cervical cancer is one of the most common gynecological malignancies in developing countries. But the cervical cancer patients with tumor prolapse are very rare. The treatment principle of cervical cancer has been written into the guide, while the management of cervical lumps prolapse associated with cervical cancer is not standardized. Every doctor has different opinions on treatment strategies. Herein, we describe the three-dimensional brachytherapy treatment for massive prolapsed cervical lumps. CASE DESCRIPTION: A 48-year-old woman diagnosed with cervical cancer developed a huge cervical mass prolapsed after defecation on the second day of chemotherapy. The mass surface was continuously bleeding and unable to return to the vagina. Therefore, uterine artery embolization interventional hemostasis was performed and then three-dimensional brachytherapy treatment was applied. The mass was necrotic and shedding and then retracted into the vagina on the 7th day after implantation treatment. Finally, the patient successfully received radical radiotherapy [pelvic and abdominal cavity external beam radiotherapy-PCTV 50.4 Gy/28 F, pelvic metastatic lymph nodes PGTVn 61.0 Gy/28 F, plus vaginal three-dimensional brachytherapy-HRCTV (D90) 27.25 Gy/4 F]. CONCLUSIONS: If cervical cancer combined with tumor prolapse is inoperable, three-dimensional implants brachytherapy seems to be an adequate therapeutic option. AME Publishing Company 2022-05 /pmc/articles/PMC9189239/ /pubmed/35706782 http://dx.doi.org/10.21037/tcr-21-2109 Text en 2022 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Case Report
Zhu, Biqing
Wu, Yaqin
Huang, Jian
He, Dan
Li, Qian
Wang, Hairong
Yang, Yongqin
Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title_full Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title_fullStr Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title_full_unstemmed Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title_short Massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
title_sort massive prolapsed cervical lumps in cervical cancer treated with three-dimensional implant brachytherapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189239/
https://www.ncbi.nlm.nih.gov/pubmed/35706782
http://dx.doi.org/10.21037/tcr-21-2109
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