Cargando…

The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis

BACKGROUND: The efficacy of pulmonary rehabilitation exercise training for patients after lung cancer resection has been controversial. We sought to evaluate the efficacy of pulmonary rehabilitation on the incidence of complications and mortality in patients after lung cancer resection. METHODS: Sea...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zelun, Cai, Renzhong, Liao, Xuqiang, Huang, Xiuming, Zhao, Chaoyang, Chen, Minbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189252/
https://www.ncbi.nlm.nih.gov/pubmed/35706789
http://dx.doi.org/10.21037/tcr-22-978
_version_ 1784725543218839552
author Chen, Zelun
Cai, Renzhong
Liao, Xuqiang
Huang, Xiuming
Zhao, Chaoyang
Chen, Minbiao
author_facet Chen, Zelun
Cai, Renzhong
Liao, Xuqiang
Huang, Xiuming
Zhao, Chaoyang
Chen, Minbiao
author_sort Chen, Zelun
collection PubMed
description BACKGROUND: The efficacy of pulmonary rehabilitation exercise training for patients after lung cancer resection has been controversial. We sought to evaluate the efficacy of pulmonary rehabilitation on the incidence of complications and mortality in patients after lung cancer resection. METHODS: Search English databases PubMed, EMBASE, Medline to obtain literature. The literature compared the effect of pulmonary rehabilitation exercise training intervention or not on the efficacy of patients after lung cancer resection, and the outcomes included postoperative complications and mortality. The quality of the included literature was assessed according to the Cochrane risk of bias assessment work. The chi-square test was used to test for heterogeneity. When there is heterogeneity, a random effect model is used; when there is no heterogeneity, a fixed effect model is used. RESULTS: A total of 9 prospective clinical studies (comprising 1,338 patients) were included in this meta-analysis. Among the patients, there were 571 cases in the rehabilitation group and 767 cases in the control group. The incidence of postoperative complications in the rehabilitation group was lower than that in the control group. The odds ratio (OR) value was 0.66 and 95% confidence interval (CI) was 0.47–0.94 (P=0.02). There was no heterogeneity among studies and no publication bias. The incidence of postoperative pulmonary complications in the rehabilitation group was lower than that in the control group, OR =0.33 (95% CI: 0.22–0.50) (P<0.00001). There was no heterogeneity among studies and no publication bias. There was no significant difference in postoperative mortality between the 2 groups (OR =0.77; 95% CI: 0.26–2.30; P=0.65). There was no heterogeneity among studies and no publication bias. DISCUSSION: Implementing pulmonary rehabilitation significantly reduced postoperative complications and the risk of pulmonary complications in lung cancer patients, but had no significant effect on mortality. Pulmonary rehabilitation exercise training is recommended for patients undergoing lung cancer resection.
format Online
Article
Text
id pubmed-9189252
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher AME Publishing Company
record_format MEDLINE/PubMed
spelling pubmed-91892522022-06-14 The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis Chen, Zelun Cai, Renzhong Liao, Xuqiang Huang, Xiuming Zhao, Chaoyang Chen, Minbiao Transl Cancer Res Original Article BACKGROUND: The efficacy of pulmonary rehabilitation exercise training for patients after lung cancer resection has been controversial. We sought to evaluate the efficacy of pulmonary rehabilitation on the incidence of complications and mortality in patients after lung cancer resection. METHODS: Search English databases PubMed, EMBASE, Medline to obtain literature. The literature compared the effect of pulmonary rehabilitation exercise training intervention or not on the efficacy of patients after lung cancer resection, and the outcomes included postoperative complications and mortality. The quality of the included literature was assessed according to the Cochrane risk of bias assessment work. The chi-square test was used to test for heterogeneity. When there is heterogeneity, a random effect model is used; when there is no heterogeneity, a fixed effect model is used. RESULTS: A total of 9 prospective clinical studies (comprising 1,338 patients) were included in this meta-analysis. Among the patients, there were 571 cases in the rehabilitation group and 767 cases in the control group. The incidence of postoperative complications in the rehabilitation group was lower than that in the control group. The odds ratio (OR) value was 0.66 and 95% confidence interval (CI) was 0.47–0.94 (P=0.02). There was no heterogeneity among studies and no publication bias. The incidence of postoperative pulmonary complications in the rehabilitation group was lower than that in the control group, OR =0.33 (95% CI: 0.22–0.50) (P<0.00001). There was no heterogeneity among studies and no publication bias. There was no significant difference in postoperative mortality between the 2 groups (OR =0.77; 95% CI: 0.26–2.30; P=0.65). There was no heterogeneity among studies and no publication bias. DISCUSSION: Implementing pulmonary rehabilitation significantly reduced postoperative complications and the risk of pulmonary complications in lung cancer patients, but had no significant effect on mortality. Pulmonary rehabilitation exercise training is recommended for patients undergoing lung cancer resection. AME Publishing Company 2022-05 /pmc/articles/PMC9189252/ /pubmed/35706789 http://dx.doi.org/10.21037/tcr-22-978 Text en 2022 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Original Article
Chen, Zelun
Cai, Renzhong
Liao, Xuqiang
Huang, Xiuming
Zhao, Chaoyang
Chen, Minbiao
The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title_full The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title_fullStr The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title_full_unstemmed The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title_short The efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
title_sort efficacy of pulmonary rehabilitation exercise training on complications and mortality after lung cancer resection: a systematic review and meta-analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189252/
https://www.ncbi.nlm.nih.gov/pubmed/35706789
http://dx.doi.org/10.21037/tcr-22-978
work_keys_str_mv AT chenzelun theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT cairenzhong theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT liaoxuqiang theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT huangxiuming theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT zhaochaoyang theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT chenminbiao theefficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT chenzelun efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT cairenzhong efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT liaoxuqiang efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT huangxiuming efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT zhaochaoyang efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis
AT chenminbiao efficacyofpulmonaryrehabilitationexercisetrainingoncomplicationsandmortalityafterlungcancerresectionasystematicreviewandmetaanalysis