Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies

Acute ischemic stroke (AIS) is a significant source of morbidity and mortality and is one of the top causes of death in the United States. Of these patients, most are elderly individuals, compared to a limited proportion of cases seen in pediatrics. AIS is classically associated with age-dependent a...

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Autores principales: Deskins, Seth J, Mamone, Matthew, Luketich, Samuel, Jennings, Arin, Downey, Sydney, Gelman, Jacob, Brant, Richard, John, Collin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189259/
https://www.ncbi.nlm.nih.gov/pubmed/35719761
http://dx.doi.org/10.7759/cureus.24982
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author Deskins, Seth J
Mamone, Matthew
Luketich, Samuel
Jennings, Arin
Downey, Sydney
Gelman, Jacob
Brant, Richard
John, Collin
author_facet Deskins, Seth J
Mamone, Matthew
Luketich, Samuel
Jennings, Arin
Downey, Sydney
Gelman, Jacob
Brant, Richard
John, Collin
author_sort Deskins, Seth J
collection PubMed
description Acute ischemic stroke (AIS) is a significant source of morbidity and mortality and is one of the top causes of death in the United States. Of these patients, most are elderly individuals, compared to a limited proportion of cases seen in pediatrics. AIS is classically associated with age-dependent atherosclerotic disease processes secondary to comorbidities such as diabetes and hypertension. When considering the pediatric population, stroke is far less common and often requires workup of other underlying etiologies that create a hypercoagulable state. Here we present a case of an eight-year-old male with a left middle cerebral artery (MCA) ischemic stroke in the setting of increased factor VIII activity and SARS-CoV-2 antibodies.
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spelling pubmed-91892592022-06-17 Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies Deskins, Seth J Mamone, Matthew Luketich, Samuel Jennings, Arin Downey, Sydney Gelman, Jacob Brant, Richard John, Collin Cureus Internal Medicine Acute ischemic stroke (AIS) is a significant source of morbidity and mortality and is one of the top causes of death in the United States. Of these patients, most are elderly individuals, compared to a limited proportion of cases seen in pediatrics. AIS is classically associated with age-dependent atherosclerotic disease processes secondary to comorbidities such as diabetes and hypertension. When considering the pediatric population, stroke is far less common and often requires workup of other underlying etiologies that create a hypercoagulable state. Here we present a case of an eight-year-old male with a left middle cerebral artery (MCA) ischemic stroke in the setting of increased factor VIII activity and SARS-CoV-2 antibodies. Cureus 2022-05-13 /pmc/articles/PMC9189259/ /pubmed/35719761 http://dx.doi.org/10.7759/cureus.24982 Text en Copyright © 2022, Deskins et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Deskins, Seth J
Mamone, Matthew
Luketich, Samuel
Jennings, Arin
Downey, Sydney
Gelman, Jacob
Brant, Richard
John, Collin
Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title_full Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title_fullStr Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title_full_unstemmed Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title_short Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies
title_sort acute ischemic stroke in an eight-year-old male with elevated factor viii activity and sars-cov-2 antibodies
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189259/
https://www.ncbi.nlm.nih.gov/pubmed/35719761
http://dx.doi.org/10.7759/cureus.24982
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