Cargando…

RASSF4 inhibits cell proliferation and increases drug sensitivity in colorectal cancer through YAP/Bcl‐2 pathway

The RASSF family proteins have been implicated in the development of human cancers. To date, the expression pattern and biological significance of RASSF4 in colorectal cancers (CRC) have not been fully investigated. In the current study, we explored expression pattern of RASSF4 in 118 CRC specimens...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Yong, Zhang, Xiaotang, Guan, Minmin, Huo, Cheng, Yu, Chunlin, Hu, Bin, Cai, Jianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189339/ https://www.ncbi.nlm.nih.gov/pubmed/35611809 http://dx.doi.org/10.1111/jcmm.17395

Ejemplares similares

SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1
por: Tian, Cong, et al.
Publicado: (2020)

Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis
por: Tian, Hui, et al.
Publicado: (2021)

The RASSF1 Gene and the Opposing Effects of the RASSF1A and RASSF1C Isoforms on Cell Proliferation and Apoptosis
por: Reeves, Mark E., et al.
Publicado: (2013)

YAP inhibits autophagy and promotes progression of colorectal cancer via upregulating Bcl-2 expression
por: Jin, Lan, et al.
Publicado: (2021)

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
por: Djos, Anna, et al.
Publicado: (2012)

RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner
por: Liang, Ying-Ying, et al.
Publicado: (2020)

Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion
por: Vlahov, Nikola, et al.
Publicado: (2015)

TET1 inhibits cell proliferation by inducing RASSF5 expression
por: Li, Bo-Tai, et al.
Publicado: (2017)

RASSF6; the Putative Tumor Suppressor of the RASSF Family
por: Iwasa, Hiroaki, et al.
Publicado: (2015)

The Intronic Long Noncoding RNA ANRASSF1 Recruits PRC2 to the RASSF1A Promoter, Reducing the Expression of RASSF1A and Increasing Cell Proliferation
por: Beckedorff, Felipe C., et al.
Publicado: (2013)

RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel
por: Guo, Jing, et al.
Publicado: (2015)

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73
por: Papaspyropoulos, Angelos, et al.
Publicado: (2018)

Dual roles of yes-associated protein (YAP) in colorectal cancer
por: Ou, Chunlin, et al.
Publicado: (2017)

RASSF Family Proteins
por: Clark, Geoffrey J., et al.
Publicado: (2012)

RASSF9 promotes NSCLC cell proliferation by activating the MEK/ERK axis
por: Yuan, Jun, et al.
Publicado: (2021)

RASSF4 Overexpression Inhibits the Proliferation, Invasion, EMT, and Wnt Signaling Pathway in Osteosarcoma Cells
por: Zhang, Minglei, et al.
Publicado: (2017)

The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth
por: Jiménez, Adriana P., et al.
Publicado: (2017)

Decreased expression of RASSF10 correlates with poor prognosis in patients with colorectal cancer
por: Ma, Junxun, et al.
Publicado: (2017)

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC
por: Chen, Xiyan, et al.
Publicado: (2017)

RASSF1 Polymorphisms in Cancer
por: Gordon, Marilyn, et al.
Publicado: (2012)

SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer
por: Shen, Hengyang, et al.
Publicado: (2021)

RASSF-1A modulates proliferation-mediated oral squamous cell carcinoma progression
por: Sun, Jianli
Publicado: (2019)

Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation
por: Yan, Zhenzhen, et al.
Publicado: (2018)

YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
por: Jiang, Linhua, et al.
Publicado: (2021)

RASSF1A methylation as a biomarker for detection of colorectal cancer and hepatocellular carcinoma
por: Li, Jian, et al.
Publicado: (2022)

The microRNA-200 family acts as an oncogene in colorectal cancer by inhibiting the tumor suppressor RASSF2
por: Carter, Jane V., et al.
Publicado: (2019)

Overexpression of RAS-Association Domain Family 6 (RASSF6) Inhibits Proliferation and Tumorigenesis in Hepatocellular Carcinoma Cells
por: Zhu, Nan, et al.
Publicado: (2017)

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias
por: Hesson, Luke B, et al.
Publicado: (2009)

Combined RASSF1A and RASSF2A Promoter Methylation Analysis as Diagnostic Biomarker for Bladder Cancer
por: Meng, Wei, et al.
Publicado: (2012)

RASSF1A Site-Specific Methylation Hotspots in Cancer and Correlation with RASSF1C and MOAP-1
por: Volodko, Natalia, et al.
Publicado: (2016)

Regulation of RASSF by non-coding RNAs in different cancers: RASSFs as masterminds of their own destiny as tumor suppressors and oncogenes
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2022)

YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells
por: SHENG, XIA, et al.
Publicado: (2015)

Loss of RASSF1A Expression in Colorectal Cancer and Its Association with K-ras Status
por: Cao, Dan, et al.
Publicado: (2013)

RASSF6 downregulation promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal cancer
por: Zhou, Rui, et al.
Publicado: (2017)

Tripartite motif containing 24 regulates cell proliferation in colorectal cancer through YAP signaling
por: Xie, Wenlin, et al.
Publicado: (2020)

Serotonin acts through YAP to promote cell proliferation: mechanism and implication in colorectal cancer progression
por: Yu, Huangfei, et al.
Publicado: (2023)

Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors
por: Malpeli, Giorgio, et al.
Publicado: (2011)

MicroRNA-181a promotes cell proliferation and inhibits apoptosis in gastric cancer by targeting RASSF1A
por: Yu, Junhui, et al.
Publicado: (2018)

RASSF6 Is Downregulated In Human Bladder Cancers And Regulates Doxorubicin Sensitivity And Mitochondrial Membrane Potential Via The Hippo Signaling Pathway
por: Tan, Shutao, et al.
Publicado: (2019)

The Drosophila RASSF Homolog Antagonizes the Hippo Pathway
por: Polesello, Cedric, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_n1cfocbq936op1oomf75tii09r