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Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design

In pelvic reconstruction surgery, the hemipelvic prosthesis can cause significant changes in stress distribution due to its high stiffness, and its solid structure is not suitable for osseointegration. The purpose of this study was to identify a novel bone mineral density screw channel and design th...

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Autores principales: Zhou, Rongqi, Xue, Haowen, Wang, Jincheng, Wang, Xiaonan, Wang, Yanbing, Zhang, Aobo, Zhang, Jiaxin, Han, Qing, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189365/
https://www.ncbi.nlm.nih.gov/pubmed/35706507
http://dx.doi.org/10.3389/fbioe.2022.892385
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author Zhou, Rongqi
Xue, Haowen
Wang, Jincheng
Wang, Xiaonan
Wang, Yanbing
Zhang, Aobo
Zhang, Jiaxin
Han, Qing
Zhao, Xin
author_facet Zhou, Rongqi
Xue, Haowen
Wang, Jincheng
Wang, Xiaonan
Wang, Yanbing
Zhang, Aobo
Zhang, Jiaxin
Han, Qing
Zhao, Xin
author_sort Zhou, Rongqi
collection PubMed
description In pelvic reconstruction surgery, the hemipelvic prosthesis can cause significant changes in stress distribution due to its high stiffness, and its solid structure is not suitable for osseointegration. The purpose of this study was to identify a novel bone mineral density screw channel and design the structure of the prosthesis so as to improve the distribution of stress, promote bone growth, and enhance the biomechanical properties of the prosthesis. The mechanical characteristics of bone mineral density screw and traditional screw were compared by finite element analysis method, and redesigned by topology optimization. The direction of the newly proposed screw channel was the posterolateral entrance of the auricular surface, ending at the contralateral sacral cape. Compared to the original group, the maximum stress of the optimized prosthesis was decreased by 24.39%, the maximum stress of the sacrum in the optimized group was decreased by 27.23%, and the average strain energy density of the sacrum in the optimized group was increased by 8.43%. On the surface of screw and connecting plate, the area with micromotion more than 28 μm is reduced by 12.17%. On the screw surface, the area with micromotion more than 28 μm is reduced by 22.9%. The newly determined screw channel and optimized prosthesis design can effectively improve the biomechanical properties of a prosthesis and the microenvironment of osseointegration. This method can provide a reference for the fixation of prostheses in clinical pelvic reconstruction.
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spelling pubmed-91893652022-06-14 Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design Zhou, Rongqi Xue, Haowen Wang, Jincheng Wang, Xiaonan Wang, Yanbing Zhang, Aobo Zhang, Jiaxin Han, Qing Zhao, Xin Front Bioeng Biotechnol Bioengineering and Biotechnology In pelvic reconstruction surgery, the hemipelvic prosthesis can cause significant changes in stress distribution due to its high stiffness, and its solid structure is not suitable for osseointegration. The purpose of this study was to identify a novel bone mineral density screw channel and design the structure of the prosthesis so as to improve the distribution of stress, promote bone growth, and enhance the biomechanical properties of the prosthesis. The mechanical characteristics of bone mineral density screw and traditional screw were compared by finite element analysis method, and redesigned by topology optimization. The direction of the newly proposed screw channel was the posterolateral entrance of the auricular surface, ending at the contralateral sacral cape. Compared to the original group, the maximum stress of the optimized prosthesis was decreased by 24.39%, the maximum stress of the sacrum in the optimized group was decreased by 27.23%, and the average strain energy density of the sacrum in the optimized group was increased by 8.43%. On the surface of screw and connecting plate, the area with micromotion more than 28 μm is reduced by 12.17%. On the screw surface, the area with micromotion more than 28 μm is reduced by 22.9%. The newly determined screw channel and optimized prosthesis design can effectively improve the biomechanical properties of a prosthesis and the microenvironment of osseointegration. This method can provide a reference for the fixation of prostheses in clinical pelvic reconstruction. Frontiers Media S.A. 2022-05-30 /pmc/articles/PMC9189365/ /pubmed/35706507 http://dx.doi.org/10.3389/fbioe.2022.892385 Text en Copyright © 2022 Zhou, Xue, Wang, Wang, Wang, Zhang, Zhang, Han and Zhao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Zhou, Rongqi
Xue, Haowen
Wang, Jincheng
Wang, Xiaonan
Wang, Yanbing
Zhang, Aobo
Zhang, Jiaxin
Han, Qing
Zhao, Xin
Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title_full Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title_fullStr Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title_full_unstemmed Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title_short Improving the Stability of a Hemipelvic Prosthesis Based on Bone Mineral Density Screw Channel and Prosthesis Optimization Design
title_sort improving the stability of a hemipelvic prosthesis based on bone mineral density screw channel and prosthesis optimization design
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189365/
https://www.ncbi.nlm.nih.gov/pubmed/35706507
http://dx.doi.org/10.3389/fbioe.2022.892385
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