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Persistent Activation of Autophagy After Cisplatin Nephrotoxicity Promotes Renal Fibrosis and Chronic Kidney Disease

Autophagy, a highly conserved catabolic pathway in eukaryotic cells, contributes to the maintenance of the homeostasis and function of the kidney. Upon acute kidney injury (AKI), autophagy is activated in renal tubular cells to act as an intrinsic protective mechanism. However, the role of autophagy...

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Detalles Bibliográficos
Autores principales:	Fu, Ying, Xiang, Yu, Wu, Wenwen, Cai, Juan, Tang, Chengyuan, Dong, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189407/ https://www.ncbi.nlm.nih.gov/pubmed/35707397 http://dx.doi.org/10.3389/fphar.2022.918732

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