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靶向CD52嵌合抗原受体T细胞的制备及其抗白血病作用研究
OBJECTIVE: To construct chimeric antigen receptor (CAR) T cells targeting CD52 (CD52 CAR-T) and validate the effect of CD52 CAR-T cells on CD52-positive leukemia. METHODS: A second-generation CD52-targeting CAR bearing 4-1BB costimulatory domain was ligated into a lentiviral vector through molecular...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189477/ https://www.ncbi.nlm.nih.gov/pubmed/35680625 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.04.003 |