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Localization of T cell clonotypes using the Visium spatial transcriptomics platform
We present a protocol to localize T cell receptor clones using the Visium spatial transcriptomics platform. This approach permits simultaneous localization of both gene expression and T cell clonotypes in situ within tissue sections. T cell receptor sequences identified by this protocol are readily...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189629/ https://www.ncbi.nlm.nih.gov/pubmed/35707680 http://dx.doi.org/10.1016/j.xpro.2022.101391 |