Peripheral blood immune cell dynamics reflect antitumor immune responses and predict clinical response to immunotherapy

BACKGROUND: Despite treatment advancements with immunotherapy, our understanding of response relies on tissue-based, static tumor features such as tumor mutation burden (TMB) and programmed death-ligand 1 (PD-L1) expression. These approaches are limited in capturing the plasticity of tumor–immune sy...

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Detalles Bibliográficos
Autores principales: Hwang, Michael, Canzoniero, Jenna Vanliere, Rosner, Samuel, Zhang, Guangfan, White, James R, Belcaid, Zineb, Cherry, Christopher, Balan, Archana, Pereira, Gavin, Curry, Alexandria, Niknafs, Noushin, Zhang, Jiajia, Smith, Kellie N, Sivapalan, Lavanya, Chaft, Jamie E, Reuss, Joshua E, Marrone, Kristen, Murray, Joseph C, Li, Qing Kay, Lam, Vincent, Levy, Benjamin P, Hann, Christine, Velculescu, Victor E, Brahmer, Julie R, Forde, Patrick M, Seiwert, Tanguy, Anagnostou, Valsamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189831/
https://www.ncbi.nlm.nih.gov/pubmed/35688557
http://dx.doi.org/10.1136/jitc-2022-004688

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