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Therapy of genomic unstable solid tumours (WHO grade 3/4)in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptides immunotherapy): study protocol for an open-label, non-randomised, prospective, single-arm trial
INTRODUCTION: Neoantigens derived from tumour somatic mutations are recognised as ideal vaccine targets. Tumour neoantigens have been studied in a wide range of tumours. Most of research on neoantigens has focused just on a unique tumour and a single mutated gene. Currently, a few studies have repor...
Autores principales: | Wang, Ling, Tang, Jiaxi, Chen, Xia, Zhao, Juan, Tang, Wanyan, Liao, Bin, Nian, Weiqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189849/ https://www.ncbi.nlm.nih.gov/pubmed/35688598 http://dx.doi.org/10.1136/bmjopen-2021-055742 |
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