Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prospective skin cancer registry ADOREG

BACKGROUND: Despite of various therapeutic strategies, treatment of patients with melanoma brain metastasis (MBM) still is a major challenge. This study aimed at investigating the impact of type and sequence of immune checkpoint blockade (ICB) and targeted therapy (TT), radiotherapy, and surgery on...

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Detalles Bibliográficos
Autores principales: Franklin, Cindy, Mohr, Peter, Bluhm, Leonie, Grimmelmann, Imke, Gutzmer, Ralf, Meier, Friedegund, Garzarolli, Marlene, Weichenthal, Michael, Pfoehler, Claudia, Herbst, Rudolf, Terheyden, Patrick, Utikal, Jochen, Ulrich, Jens, Debus, Dirk, Haferkamp, Sebastian, Kaatz, Martin, Forschner, Andrea, Leiter, Ulrike, Nashan, Dorothee, Kreuter, Alexander, Sachse, Michael, Welzel, Julia, Heinzerling, Lucie, Meiss, Frank, Weishaupt, Carsten, Gambichler, Thilo, Weyandt, Gerhard, Dippel, Edgar, Schatton, Kerstin, Celik, Eren, Trommer, Maike, Helfrich, Iris, Roesch, Alexander, Zimmer, Lisa, Livingstone, Elisabeth, Schadendorf, Dirk, Horn, Susanne, Ugurel, Selma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189852/
https://www.ncbi.nlm.nih.gov/pubmed/35688555
http://dx.doi.org/10.1136/jitc-2022-004509

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