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Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells

BACKGROUND: Dendritic cells (DCs) are professional antigen presenting cells that initiate immune defense to pathogens and tumor cells. Human tumors contain only few DCs that mostly display a non-activated phenotype. Hence, activation of tumor-associated DCs may improve efficacy of cancer immunothera...

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Detalles Bibliográficos
Autores principales:	He, Mi, Soni, Bhavesh, Schwalie, Petra C, Hüsser, Tamara, Waltzinger, Caroline, De Silva, Duvini, Prinz, Ylva, Krümpelmann, Laura, Calabro, Samuele, Matos, Ines, Trumpfheller, Christine, Bacac, Marina, Umaña, Pablo, Levesque, Mitchell P, Dummer, Reinhard, van den Broek, Maries, Gasser, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189853/ https://www.ncbi.nlm.nih.gov/pubmed/35688559 http://dx.doi.org/10.1136/jitc-2021-004268

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