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LTBK-06. Memantine increases dendritic arborization and integration of immature neurons after cranial irradiation
Cranial irradiation (IR) is a cornerstone in the treatment of high-grade pediatric brain tumors. While lifesaving, it is associated with severe sequalae in 50-90 % of the survivors, as they often show disabling cognitive dysfunction, declined IQ, impaired processing speed, anxiety and posttraumatic...
Autores principales: | Zisiadis, Georgios, Rodrigues, Carlos, Pizzirusso, Giusy, Arroyo-García, Luis, Osman, Ahmed, Blomgren, Klas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189947/ http://dx.doi.org/10.1093/neuonc/noac079.718 |
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