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Interpreting Mendelian-randomization estimates of the effects of categorical exposures such as disease status and educational attainment

BACKGROUND: Mendelian randomization has been previously used to estimate the effects of binary and ordinal categorical exposures—e.g. Type 2 diabetes or educational attainment defined by qualification—on outcomes. Binary and categorical phenotypes can be modelled in terms of liability—an underlying...

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Detalles Bibliográficos
Autores principales:	Howe, Laurence J, Tudball, Matthew, Davey Smith, George, Davies, Neil M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189950/ https://www.ncbi.nlm.nih.gov/pubmed/34570226 http://dx.doi.org/10.1093/ije/dyab208

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