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Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription

The small GTPase Cdc42 exists in the form of two alternatively spliced variants that are modified by hydrophobic chains: the ubiquitously expressed Cdc42-prenyl and a brain-specific isoform that can be palmitoylated, Cdc42-palm. Our previous work demonstrated that Cdc42-palm can be palmitoylated at...

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Detalles Bibliográficos
Autores principales: Wirth, Alexander, Labus, Josephine, Abdel Galil, Dalia, Schill, Yvonne, Schmidt, Silke, Bunke, Tania, Gorinski, Nataliya, Yokoi, Norihiko, Fukata, Masaki, Ponimaskin, Evgeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190017/
https://www.ncbi.nlm.nih.gov/pubmed/35597282
http://dx.doi.org/10.1016/j.jbc.2022.102048

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