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MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation

The melanocortin receptor accessory protein 2 (MRAP2) is essential for several physiological functions of the ghrelin receptor growth hormone secretagogue receptor 1a (GHSR1a), including increasing appetite and suppressing insulin secretion. In the absence of MRAP2, GHSR1a displays high constitutive...

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Detalles Bibliográficos
Autores principales:	Rouault, Alix A.J., Buscaglia, Paul, Sebag, Julien A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190059/ https://www.ncbi.nlm.nih.gov/pubmed/35605660 http://dx.doi.org/10.1016/j.jbc.2022.102057

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