Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case

Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms...

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Detalles Bibliográficos
Autores principales: Ayub, Shahana, Saboor, Sundas, Usmani, Sadia, Javed, Sana, Tonpouwo, Gauvain Kankeu, Ahmed, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: College of Psychiatric & Neurologic Pharmacists 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190271/
https://www.ncbi.nlm.nih.gov/pubmed/35801162
http://dx.doi.org/10.9740/mhc.2022.06.214
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author Ayub, Shahana
Saboor, Sundas
Usmani, Sadia
Javed, Sana
Tonpouwo, Gauvain Kankeu
Ahmed, Saeed
author_facet Ayub, Shahana
Saboor, Sundas
Usmani, Sadia
Javed, Sana
Tonpouwo, Gauvain Kankeu
Ahmed, Saeed
author_sort Ayub, Shahana
collection PubMed
description Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted.
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spelling pubmed-91902712022-07-06 Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case Ayub, Shahana Saboor, Sundas Usmani, Sadia Javed, Sana Tonpouwo, Gauvain Kankeu Ahmed, Saeed Ment Health Clin Case Reports Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted. College of Psychiatric & Neurologic Pharmacists 2022-06-10 /pmc/articles/PMC9190271/ /pubmed/35801162 http://dx.doi.org/10.9740/mhc.2022.06.214 Text en © 2022 AAPP. The Mental Health Clinician is a publication of the American Association of Psychiatric Pharmacists. https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Ayub, Shahana
Saboor, Sundas
Usmani, Sadia
Javed, Sana
Tonpouwo, Gauvain Kankeu
Ahmed, Saeed
Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title_full Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title_fullStr Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title_full_unstemmed Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title_short Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
title_sort lithium toxicity following roux-en-y gastric bypass: mini review and illustrative case
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190271/
https://www.ncbi.nlm.nih.gov/pubmed/35801162
http://dx.doi.org/10.9740/mhc.2022.06.214
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