Redefining the Foreign Antigen and Self-Driven Memory CD4(+) T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses

Under steady-state conditions, conventional CD4(+) T lymphocytes are classically divided into naïve (CD44(lo) CD62L(hi)) and memory (CD44(hi) CD62L(lo)) cell compartments. While the latter population is presumed to comprise a mixture of distinct subpopulations of explicit foreign antigen (Ag)-specif...

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Detalles Bibliográficos
Autores principales: Kawabe, Takeshi, Ciucci, Thomas, Kim, Kwang Soon, Tayama, Shunichi, Kawajiri, Akihisa, Suzuki, Takumi, Tanaka, Riou, Ishii, Naoto, Jankovic, Dragana, Zhu, Jinfang, Sprent, Jonathan, Bosselut, Rémy, Sher, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190281/
https://www.ncbi.nlm.nih.gov/pubmed/35707543
http://dx.doi.org/10.3389/fimmu.2022.870542

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