Cargando…

Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials

BACKGROUND: The role of metformin in the treatment of adolescents with type 1 diabetes mellitus (T1DM) remains controversial. We conducted this updated meta-analysis to generate a comprehensive assessment regarding the effect and safety of metformin in treating adolescents with T1DM. METHODS: We sys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ying, Chen, Hongbo, Li, Hui, Li, Liman, Wu, Jin, Li, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190285/ https://www.ncbi.nlm.nih.gov/pubmed/35707462 http://dx.doi.org/10.3389/fendo.2022.878585

Ejemplares similares

Effect of Metformin on Testosterone Levels in Male Patients With Type 2 Diabetes Mellitus Treated With Insulin
por: Cai, Tingting, et al.
Publicado: (2021)

Comparison of Clinical Efficacy and Safety of Metformin Sustained-Release Tablet (II) (Dulening) and Metformin Tablet (Glucophage) in Treatment of Type 2 Diabetes Mellitus
por: Guo, Li-xin, et al.
Publicado: (2021)

Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial
por: Lundby-Christensen, Louise, et al.
Publicado: (2016)

Association of Preadmission Metformin Use and Prognosis in Patients With Sepsis and Diabetes Mellitus: A Systematic Review and Meta-Analysis
por: Li, Yuanzhe, et al.
Publicado: (2021)

Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis
por: Guo, Lanlan, et al.
Publicado: (2019)

Cost-Effectiveness of Dipeptidylpeptidase-4 Inhibitors Added to Metformin in Patients With Type 2 Diabetes in China
por: Lin, Wen-Qiang, et al.
Publicado: (2021)

Metformin treatment and risk of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus in Beijing, China
por: Yang, Ruotong, et al.
Publicado: (2023)

Efficacy of Metformin for Benign Thyroid Nodules in Subjects With Insulin Resistance: A Systematic Review and Meta-Analysis
por: Sui, Miao, et al.
Publicado: (2018)

Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: a randomised trial
por: Wilding, J P H, et al.
Publicado: (2013)

Gastrointestinal adverse events of metformin treatment in patients with type 2 diabetes mellitus: A systematic review, meta-analysis and meta-regression of randomized controlled trials
por: Nabrdalik, Katarzyna, et al.
Publicado: (2022)

Effects of mulberry twig alkaloids(Sangzhi alkaloids) and metformin on blood glucose fluctuations in combination with premixed insulin-treated patients with type 2 diabetes
por: Meng, Ziyu, et al.
Publicado: (2023)

Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review
por: Xie, Zeyu, et al.
Publicado: (2023)

Anti-diabetic combination therapy with pioglitazone or glimepiride added to metformin on the AGE-RAGE axis: a randomized prospective study
por: Ragazzi, Eugenio, et al.
Publicado: (2023)

Metformin Use and Leukemia Risk in Patients With Type 2 Diabetes Mellitus
por: Tseng, Chin-Hsiao
Publicado: (2020)

Acupuncture combined with metformin versus metformin alone to improve pregnancy rate in polycystic ovary syndrome: A systematic review and meta-analysis
por: Chen, Xin, et al.
Publicado: (2022)

Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial
por: Yang, Daizhi, et al.
Publicado: (2020)

Metformin combined with spironolactone vs. metformin alone in polycystic ovary syndrome: a meta-analysis
por: Zeng, Huamin, et al.
Publicado: (2023)

Association of subclass distribution of insulin antibody with glucose control in insulin-treated type 2 diabetes mellitus: a retrospective observational study
por: Chen, Shuang, et al.
Publicado: (2023)

Effectiveness and safety of glimepiride and iDPP4, associated with metformin in second line pharmacotherapy of type 2 diabetes mellitus: systematic review and meta‐analysis
por: Amate, JM., et al.
Publicado: (2015)

Metformin therapy in pediatric type 2 diabetes mellitus and its comorbidities: A review
por: Alfaraidi, Haifa, et al.
Publicado: (2023)

Effects of Metformin on Reproductive, Endocrine, and Metabolic Characteristics of Female Offspring in a Rat Model of Letrozole-Induced Polycystic Ovarian Syndrome With Insulin Resistance
por: Xie, Yidong, et al.
Publicado: (2021)

The safety of sotagliflozin in the therapy of diabetes mellitus type 1 and type 2: A meta-analysis of randomized trials
por: Zhou, Feifei, et al.
Publicado: (2022)

The effect of Chinese herbal formulas combined with metformin on modulating the gut microbiota in the amelioration of type 2 diabetes mellitus: A systematic review and meta-analysis
por: Xu, Yunxi, et al.
Publicado: (2022)

Impact of Insulin Resistance on Cardiometabolic Risk Factors and an Anthropometry-Based Predictive Nomogram for Insulin Resistance Among Adolescents in China
por: Du, Runyu, et al.
Publicado: (2022)

The association between insulin therapy and depression in patients with type 2 diabetes mellitus: a meta-analysis
por: Bai, Xiaosu, et al.
Publicado: (2018)

An update of the consensus statement on insulin resistance in children 2010
por: Tagi, Veronica Maria, et al.
Publicado: (2022)

Insulin Degludec Versus Insulin Glargine on Glycemic Variability in Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
por: Yang, Yunjiao, et al.
Publicado: (2022)

Insulin-Like Growth Factor Axis Biomarkers and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
por: Wang, Xi-Rui, et al.
Publicado: (2019)

Metformin Use Is Not Associated With B(12) Deficiency or Neuropathy in Patients With Type 2 Diabetes Mellitus in Qatar
por: Elhadd, Tarik, et al.
Publicado: (2018)

Ferroptosis and its potential role in gestational diabetes mellitus: updated evidence from pathogenesis to therapy
por: Zhao, Yan, et al.
Publicado: (2023)

Efficacy and safety of traditional Chinese medicines combined with conventional Western medicines in the treatment of type 2 diabetes mellitus: a network meta-analysis of randomized controlled trials
por: Ma, Kaile, et al.
Publicado: (2023)

Safety and efficacy of insulin glargine 300 u/mL compared with other basal insulin therapies in patients with type 2 diabetes mellitus: a network meta-analysis
por: Freemantle, Nick, et al.
Publicado: (2016)

The efficacy and safety of evogliptin for type 2 diabetes mellitus: A systematic review and meta-analysis
por: Tang, Qizhi, et al.
Publicado: (2022)

Efficacy and safety of teneligliptin added to metformin in Chinese patients with type 2 diabetes mellitus inadequately controlled with metformin: A phase 3, randomized, double‐blind, placebo‐controlled study
por: Ji, Linong, et al.
Publicado: (2021)

Real-world outcomes of US employees with type 2 diabetes mellitus treated with insulin glargine or neutral protamine Hagedorn insulin: a comparative retrospective database study
por: Wang, Li, et al.
Publicado: (2013)

Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial
por: Lundby-Christensen, Louise, et al.
Publicado: (2016)

Vascular Complication in Adolescents With Diabetes Mellitus
por: Graves, Lara E., et al.
Publicado: (2020)

ABCA1 69C>T Polymorphism and the Risk of Type 2 Diabetes Mellitus: A Systematic Review and Updated Meta-Analysis
por: Yoon, Ha Young, et al.
Publicado: (2021)

Effects of Metformin on TSH Levels and Benign Nodular Goiter Volume in Patients Without Insulin Resistance or Iodine Insufficiency
por: dos Santos, Patricia Borges, et al.
Publicado: (2019)

GDF-15 as a Weight Watcher for Diabetic and Non-Diabetic People Treated With Metformin
por: Ouyang, Jing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0drs7l2lhr42g2gpeb2mafgafh