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Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India

Background Gallbladder stones are more common in some regions of the world than others. Gallstones that are asymptomatic might be discovered as an afterthought during a regular ultrasound scan for another abdominal ailment. The changing incidence in India is mostly due to westernization and the avai...

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Autores principales: Patel, Aditya M, Yeola, Meenakshi, Mahakalkar, Chandrashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190443/
https://www.ncbi.nlm.nih.gov/pubmed/35719762
http://dx.doi.org/10.7759/cureus.24993
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author Patel, Aditya M
Yeola, Meenakshi
Mahakalkar, Chandrashekhar
author_facet Patel, Aditya M
Yeola, Meenakshi
Mahakalkar, Chandrashekhar
author_sort Patel, Aditya M
collection PubMed
description Background Gallbladder stones are more common in some regions of the world than others. Gallstones that are asymptomatic might be discovered as an afterthought during a regular ultrasound scan for another abdominal ailment. The changing incidence in India is mostly due to westernization and the availability of ultrasonography in both urban and rural areas, as well as increased affordability owing to changes in the socio-economic structure and the budget of investigations. This study aims to know the prevalence of gallstone disease as well as the risk factors that contribute to its development in central India. Method A single-center, cross-sectional observational study was conducted. Seventy-two radiologically diagnosed cases of gallstone disease irrespective of age, gender, and comorbid condition were included in the study. Result Seventy-two cases of gallstone were included in the research. The highest age-specific incidence of gallstone was in the fifth and sixth decades with the maximum incidence in the sixth decade. Females had a higher incidence of gallstone formation. The pain was the earliest symptom but we found that 41.67% patients had asymptomatic gallstones. A family history of gallstone disease is found positive in 69.44% of the patients who also had an increased risk of gallstone. 22.22% patient were only diabetic, 6.95% were only hypertensive and 20.83% were both diabetic + hypertensive. Comorbidity has a high prevalence of gallstone disease. Obesity has a significant link to gallstone disease, with BMI being one of the most important indicators of obesity. Conclusion The prevalence of asymptomatic gallstones is relatively high in central India. We strongly recommend ultrasonography as a screening modality in patients with older age group, female gender, high cholesterol level, family history of gallstones, sickle cell disease, increased BMI and co-morbidities like diabetes or hypertension for early detection of gallstones formation.
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spelling pubmed-91904432022-06-17 Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India Patel, Aditya M Yeola, Meenakshi Mahakalkar, Chandrashekhar Cureus Gastroenterology Background Gallbladder stones are more common in some regions of the world than others. Gallstones that are asymptomatic might be discovered as an afterthought during a regular ultrasound scan for another abdominal ailment. The changing incidence in India is mostly due to westernization and the availability of ultrasonography in both urban and rural areas, as well as increased affordability owing to changes in the socio-economic structure and the budget of investigations. This study aims to know the prevalence of gallstone disease as well as the risk factors that contribute to its development in central India. Method A single-center, cross-sectional observational study was conducted. Seventy-two radiologically diagnosed cases of gallstone disease irrespective of age, gender, and comorbid condition were included in the study. Result Seventy-two cases of gallstone were included in the research. The highest age-specific incidence of gallstone was in the fifth and sixth decades with the maximum incidence in the sixth decade. Females had a higher incidence of gallstone formation. The pain was the earliest symptom but we found that 41.67% patients had asymptomatic gallstones. A family history of gallstone disease is found positive in 69.44% of the patients who also had an increased risk of gallstone. 22.22% patient were only diabetic, 6.95% were only hypertensive and 20.83% were both diabetic + hypertensive. Comorbidity has a high prevalence of gallstone disease. Obesity has a significant link to gallstone disease, with BMI being one of the most important indicators of obesity. Conclusion The prevalence of asymptomatic gallstones is relatively high in central India. We strongly recommend ultrasonography as a screening modality in patients with older age group, female gender, high cholesterol level, family history of gallstones, sickle cell disease, increased BMI and co-morbidities like diabetes or hypertension for early detection of gallstones formation. Cureus 2022-05-14 /pmc/articles/PMC9190443/ /pubmed/35719762 http://dx.doi.org/10.7759/cureus.24993 Text en Copyright © 2022, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Patel, Aditya M
Yeola, Meenakshi
Mahakalkar, Chandrashekhar
Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title_full Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title_fullStr Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title_full_unstemmed Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title_short Demographic and Risk Factor Profile in Patients of Gallstone Disease in Central India
title_sort demographic and risk factor profile in patients of gallstone disease in central india
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190443/
https://www.ncbi.nlm.nih.gov/pubmed/35719762
http://dx.doi.org/10.7759/cureus.24993
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