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RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies

MOTIVATION: Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucle...

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Detalles Bibliográficos
Autores principales: Segura, Joan, Rose, Yana, Bittrich, Sebastian, Burley, Stephen K, Duarte, Jose M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191206/
https://www.ncbi.nlm.nih.gov/pubmed/35543462
http://dx.doi.org/10.1093/bioinformatics/btac317
Descripción
Sumario:MOTIVATION: Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level. RESULTS: We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies. AVAILABILITY AND IMPLEMENTATION: https://github.com/rcsb/rcsb-saguaro-3d. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.