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Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study

Several large-scale studies have assessed the endovascular and surgical treatments for nonocclusive mesenteric ischemia (NOMI); nonetheless, the prognostic factors for NOMI remain unclear. In this single-center study, we retrospectively reviewed the electronic medical records of 197, 149 patients we...

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Autores principales: Murata, Takaaki, Kawachi, Jun, Igarashi, Yuto, Suno, Yuma, Nishida, Tomoki, Miyake, Katsunori, Isogai, Naoko, Fukai, Ryuta, Kashiwagi, Hiroyuki, Shimoyama, Rai, Hirata, Masahiro, Shinozaki, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191297/
https://www.ncbi.nlm.nih.gov/pubmed/35049224
http://dx.doi.org/10.1097/MD.0000000000028056
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author Murata, Takaaki
Kawachi, Jun
Igarashi, Yuto
Suno, Yuma
Nishida, Tomoki
Miyake, Katsunori
Isogai, Naoko
Fukai, Ryuta
Kashiwagi, Hiroyuki
Shimoyama, Rai
Hirata, Masahiro
Shinozaki, Nobuaki
author_facet Murata, Takaaki
Kawachi, Jun
Igarashi, Yuto
Suno, Yuma
Nishida, Tomoki
Miyake, Katsunori
Isogai, Naoko
Fukai, Ryuta
Kashiwagi, Hiroyuki
Shimoyama, Rai
Hirata, Masahiro
Shinozaki, Nobuaki
author_sort Murata, Takaaki
collection PubMed
description Several large-scale studies have assessed the endovascular and surgical treatments for nonocclusive mesenteric ischemia (NOMI); nonetheless, the prognostic factors for NOMI remain unclear. In this single-center study, we retrospectively reviewed the electronic medical records of 197, 149 patients were retrieved from the inpatient database of our hospital from January 2011 to January 2020; 79 patients with NOMI were observed. A total of 44 patients who underwent laparotomy were statistically analyzed and divided into the survivor and non-survivor groups. Prognostic factors were compared between the 2 groups. Exploratory laparotomy based on a second-look surgery was the first treatment choice. The overall mortality rate was 61.3%, with a male-to-female ratio of 1.6:1. The median Sequential Organ Failure Assessment (SOFA) score was 11.06 [5.75-17.25]. The median SOFA score was 5 [interquartile range: 3-8] in the survivor group and 14.8 [interquartile range: 10.5-19] in the non-survivor group. The log-rank test showed a significant difference in the presence of diabetes mellitus (P = .025), hypoglycemia (P = .001), SOFA score ≥10 (P < .001), hemoglobin levels ≥11 g/dL (P = .003), platelet count ≥12.9 × 10(4)/μL (P = .01), lactate levels ≥2.6 mmol/L (P = .005), and base excess <-3.0 (P < .023). Multivariate analysis using the factors with significant differences revealed that SOFA score ≥10 (hazard ratio for death, 1.199; 95% confidence interval, 1.101-1.305; P < .001) was an independent prognostic factor. The SOFA score can be used to assess disease severity. A SOFA score of ≥10 may be associated with increased mortality.
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spelling pubmed-91912972022-06-13 Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study Murata, Takaaki Kawachi, Jun Igarashi, Yuto Suno, Yuma Nishida, Tomoki Miyake, Katsunori Isogai, Naoko Fukai, Ryuta Kashiwagi, Hiroyuki Shimoyama, Rai Hirata, Masahiro Shinozaki, Nobuaki Medicine (Baltimore) 7100 Several large-scale studies have assessed the endovascular and surgical treatments for nonocclusive mesenteric ischemia (NOMI); nonetheless, the prognostic factors for NOMI remain unclear. In this single-center study, we retrospectively reviewed the electronic medical records of 197, 149 patients were retrieved from the inpatient database of our hospital from January 2011 to January 2020; 79 patients with NOMI were observed. A total of 44 patients who underwent laparotomy were statistically analyzed and divided into the survivor and non-survivor groups. Prognostic factors were compared between the 2 groups. Exploratory laparotomy based on a second-look surgery was the first treatment choice. The overall mortality rate was 61.3%, with a male-to-female ratio of 1.6:1. The median Sequential Organ Failure Assessment (SOFA) score was 11.06 [5.75-17.25]. The median SOFA score was 5 [interquartile range: 3-8] in the survivor group and 14.8 [interquartile range: 10.5-19] in the non-survivor group. The log-rank test showed a significant difference in the presence of diabetes mellitus (P = .025), hypoglycemia (P = .001), SOFA score ≥10 (P < .001), hemoglobin levels ≥11 g/dL (P = .003), platelet count ≥12.9 × 10(4)/μL (P = .01), lactate levels ≥2.6 mmol/L (P = .005), and base excess <-3.0 (P < .023). Multivariate analysis using the factors with significant differences revealed that SOFA score ≥10 (hazard ratio for death, 1.199; 95% confidence interval, 1.101-1.305; P < .001) was an independent prognostic factor. The SOFA score can be used to assess disease severity. A SOFA score of ≥10 may be associated with increased mortality. Lippincott Williams & Wilkins 2021-12-03 /pmc/articles/PMC9191297/ /pubmed/35049224 http://dx.doi.org/10.1097/MD.0000000000028056 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 7100
Murata, Takaaki
Kawachi, Jun
Igarashi, Yuto
Suno, Yuma
Nishida, Tomoki
Miyake, Katsunori
Isogai, Naoko
Fukai, Ryuta
Kashiwagi, Hiroyuki
Shimoyama, Rai
Hirata, Masahiro
Shinozaki, Nobuaki
Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title_full Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title_fullStr Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title_full_unstemmed Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title_short Monitoring the Sequential Organ Failure Assessment score in nonocclusive mesenteric ischemia increases the survival rate: A single-center observational study
title_sort monitoring the sequential organ failure assessment score in nonocclusive mesenteric ischemia increases the survival rate: a single-center observational study
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191297/
https://www.ncbi.nlm.nih.gov/pubmed/35049224
http://dx.doi.org/10.1097/MD.0000000000028056
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