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The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition
Helicases are multifunctional motor proteins with the primary task of separating nucleic acid duplexes. These enzymes often exist in distinct oligomeric forms and play essential roles during nucleic acid metabolism. Whether there is a correlation between their oligomeric state and cellular function,...
Autores principales: | Bi, Lulu, Qin, Zhenheng, Wang, Teng, Li, Yanan, Jia, Xinshuo, Zhang, Xia, Hou, Xi-Miao, Modesti, Mauro, Xi, Xu-Guang, Sun, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191346/ https://www.ncbi.nlm.nih.gov/pubmed/35658074 http://dx.doi.org/10.1073/pnas.2116462119 |
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