Cargando…
Clinico-radiological features of brain metastases from thyroid cancer
The brain is an unusual site for distant metastases of thyroid cancer. The radiological features of brain metastases (BMs) have rarely been reported. Hemorrhage is frequently noted in BMs from thyroid cancer. This study aimed to investigate the clinico-radiological features of BMs from thyroid cance...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191371/ https://www.ncbi.nlm.nih.gov/pubmed/35049229 http://dx.doi.org/10.1097/MD.0000000000028069 |
_version_ | 1784725997119078400 |
---|---|
author | Kim, Song Soo Kim, Seok-Mo Park, Mina Suh, Sang Hyun Ahn, Sung Jun |
author_facet | Kim, Song Soo Kim, Seok-Mo Park, Mina Suh, Sang Hyun Ahn, Sung Jun |
author_sort | Kim, Song Soo |
collection | PubMed |
description | The brain is an unusual site for distant metastases of thyroid cancer. The radiological features of brain metastases (BMs) have rarely been reported. Hemorrhage is frequently noted in BMs from thyroid cancer. This study aimed to investigate the clinico-radiological features of BMs from thyroid cancer and to determine the risk factors to predict BM hemorrhage. We retrospectively evaluated the MR images of 35 patients with BMs from thyroid cancer at our hospital from 2013 to 2020. The number, size, site, presence of extra-cranial metastasis, presence of perilesional edema, intra-tumoral hemorrhage, enhancement pattern, and presence of diffusion restriction on MRI were described. We further classified the thyroid cancers into hemorrhagic and nonhemorrhagic groups to investigate the factors associated with hemorrhage. 54.29% of patients with thyroid BMs (19/35) had neurologic symptoms. 94.29% of patients (33/35) had extra-cranial metastases. The most common histology of primary thyroid cancer was papillary thyroid cancer (71.43%, 25/35), followed by anaplastic thyroid cancer (22.86%, 8/35). Thyroid cancer BMs were located mostly in the supra-tentorium (51.43%, 18/35) or both the supra and infra-tentorium (45.71%, 16/35). 60% of patients (21/35) showed hemorrhage within the BMs. The strongest predictor for BM hemorrhage was tumor size (variable importance: 50). Thyroid cancer BMs exhibit a bleeding tendency. Furthermore, larger BMs are more likely to have an intra-tumoral hemorrhage. |
format | Online Article Text |
id | pubmed-9191371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-91913712022-06-13 Clinico-radiological features of brain metastases from thyroid cancer Kim, Song Soo Kim, Seok-Mo Park, Mina Suh, Sang Hyun Ahn, Sung Jun Medicine (Baltimore) 6800 The brain is an unusual site for distant metastases of thyroid cancer. The radiological features of brain metastases (BMs) have rarely been reported. Hemorrhage is frequently noted in BMs from thyroid cancer. This study aimed to investigate the clinico-radiological features of BMs from thyroid cancer and to determine the risk factors to predict BM hemorrhage. We retrospectively evaluated the MR images of 35 patients with BMs from thyroid cancer at our hospital from 2013 to 2020. The number, size, site, presence of extra-cranial metastasis, presence of perilesional edema, intra-tumoral hemorrhage, enhancement pattern, and presence of diffusion restriction on MRI were described. We further classified the thyroid cancers into hemorrhagic and nonhemorrhagic groups to investigate the factors associated with hemorrhage. 54.29% of patients with thyroid BMs (19/35) had neurologic symptoms. 94.29% of patients (33/35) had extra-cranial metastases. The most common histology of primary thyroid cancer was papillary thyroid cancer (71.43%, 25/35), followed by anaplastic thyroid cancer (22.86%, 8/35). Thyroid cancer BMs were located mostly in the supra-tentorium (51.43%, 18/35) or both the supra and infra-tentorium (45.71%, 16/35). 60% of patients (21/35) showed hemorrhage within the BMs. The strongest predictor for BM hemorrhage was tumor size (variable importance: 50). Thyroid cancer BMs exhibit a bleeding tendency. Furthermore, larger BMs are more likely to have an intra-tumoral hemorrhage. Lippincott Williams & Wilkins 2021-12-03 /pmc/articles/PMC9191371/ /pubmed/35049229 http://dx.doi.org/10.1097/MD.0000000000028069 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | 6800 Kim, Song Soo Kim, Seok-Mo Park, Mina Suh, Sang Hyun Ahn, Sung Jun Clinico-radiological features of brain metastases from thyroid cancer |
title | Clinico-radiological features of brain metastases from thyroid cancer |
title_full | Clinico-radiological features of brain metastases from thyroid cancer |
title_fullStr | Clinico-radiological features of brain metastases from thyroid cancer |
title_full_unstemmed | Clinico-radiological features of brain metastases from thyroid cancer |
title_short | Clinico-radiological features of brain metastases from thyroid cancer |
title_sort | clinico-radiological features of brain metastases from thyroid cancer |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191371/ https://www.ncbi.nlm.nih.gov/pubmed/35049229 http://dx.doi.org/10.1097/MD.0000000000028069 |
work_keys_str_mv | AT kimsongsoo clinicoradiologicalfeaturesofbrainmetastasesfromthyroidcancer AT kimseokmo clinicoradiologicalfeaturesofbrainmetastasesfromthyroidcancer AT parkmina clinicoradiologicalfeaturesofbrainmetastasesfromthyroidcancer AT suhsanghyun clinicoradiologicalfeaturesofbrainmetastasesfromthyroidcancer AT ahnsungjun clinicoradiologicalfeaturesofbrainmetastasesfromthyroidcancer |